Abstract

Varicella zoster virus VZV causes chickenpox a self-limited disease with disseminated skin lesions that occurs mostly in childhood It usually persists symtomatically in the dorsal root ganglia of anyone who has had chickenpox It reactivates from its dormant state and travel along the sensory nerve causing vesicular lesions in the dermatome supplied by that nerve in about 25 of people who had chickenpox in their childhood These lesions known as Herpes zoster or shingles and it causes a painful eruption of a rash usually unilaterally It occurs more frequently in older adults and immunocompromised individuals 1 HZ afflicts millions of older adults worldwide and causes significant suffering because of acute and chronic pain or postherpetic neuralgia PHN 2 It is believed that the potential risk factors for HZ are aging and suppression of cellular immunity 1 2 3 They treat HZ with topical application of Acyclovir 5 cream In severe cases they prescribe Acyclovir 800 mg 5 times daily for 7 to 10 days and they recommend taking plenty of water along with medication 4 Therefore it is for patients with normal cardiac and kidney function