Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats

Mostapha Bachir bey; Rekia Sidhoum; Latifa Halli; Othmane Yalaoui; Asma Belkadi

Authors

Mostapha Bachir bey
Rekia Sidhoum
Latifa Halli
Othmane Yalaoui
Asma Belkadi

Keywords:

rustyback; phenolic composition; chlorogenic acid; biological property; in vivo activity

Abstract

Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by High-performance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher that of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.

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How to Cite

Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats. (2020). Global Journal of Medical Research, 20(B6), 27-32. https://medicalresearchjournal.org/index.php/GJMR/article/view/2198

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