Aim: To evaluate the use of posterior instrumentation with transpedicular screw and connecting rods in management of post-traumatic unstable thoracolumbar spine fractures. Methods: 20 patients with post-traumatic instability of thoracolumbar spine were included in our study. The spinal stability was assessed by the thoracolumbar injury severity scoring. All patients underwent an open reduction internal fixation by the posterior approach. The localisation of pedicles was done using intraoperative imaging. The assessment of neurological status of the patients was done using the ASIA grading scale and other complications were assessed and noted up to 6 months. Results: 20 patients with unstable thoracolumbar injuries were managed with pedicle screws and rods. Males were affected more than Females. The most common type was AO Type A and L1 was the level most affected. None of the patients deteriorated after surgery. 15 patients with incomplete cord injury showed at least one frankel grade improvement. 4 patients with complete cord injury showed no improvement.