Abstract

Objective: The present study was designed to investigate the glucose uptake of (antidiabetic activity) crude n-hexane,ethanol, methanol and aqueous leaf extracts of Cardiospermum Halicacabum. Methods: of Cardiospermum Halicacabumleaf extracts were subjected to inhibitory effect of glucose utilization using specific standard in vitro procedure. Results: results in four different leaf extracts revealed that, the methanol extract at a concentration of 50g plant extract/l was found to be more potent than other extracts with the lowest mean glucose concentration of 201#xB1;1.69 mg/dl at the end of 27 hrs. Conclusions: The present findings suggest that, the methanolic extract showed a significant inhibitory effect on glucose diffusion in vitro thus validating the traditional claim of the plant.