Preliminary Investigation on Anti Typhoid Properties of Acacia Nilotica Leaf Extract

Sarkiyayi  S.

Authors

Sarkiyayi S.

Keywords:

typhoid fever, anti typhoid, acacia nilotica, salmonella typhi and ld

Abstract

Anti typhoid properties of methanol leaves extract of Acacia nilotica was investigated. The phytochemical screenings for detection of the presence of bioactive constituents were carried out. A of mice with Salmonella typhi parasites treating them with leave extract of Acacia nilotica followed by widal tests. The phytochemical screening of the methanol leave extract of Acacia nilotica revealed the presence of alkaloid, anthraquinone, carbohydrates, cardiac glycosides, flavonoid, saponin, tannins and terpens. The leaves extract of Acacia nilotica has possess some acute toxicity effect on animals (mice) at a dose of ( inhibitory activities against Salmonella typhi. It is interesting to note the widal test titer valve was found to be 140 for the treated group while the untreated group had titer value of 1160 the plant leaves extract was effective as anti typhoid agent against salmonella typhi on mice infected with typhoid parasites.

Downloads

How to Cite

Preliminary Investigation on Anti Typhoid Properties of Acacia Nilotica Leaf Extract. (2013). Global Journal of Medical Research, 13(F5), 11-15. https://medicalresearchjournal.org/index.php/GJMR/article/view/458

Download Citation

References

D Akinpelu, D Kolawole (2004) Phytochemcials and antimicrobial activity of leaf extract of Piiositigma thoriningi (Schum). 7, 64-70.

F Aussie (2006) the properties of Acacia spices and their uses. 152-185.

N Azu, R Onyeagba (2007) Antimicrobial properties of extracts of Allium cepa (onions) and Zingiber officinale (ginger) on Escherichia coli, and Bacillus subtilis. 3(2), 277-286.

T Ayogu, E Amadi (2009) Studies On The Antibacterial Activities Of Medicinal Plants On Typhoid Fever Organism. 7(2).

Fiona Cooke, John Wain, E Threlfall (2006) Fluoroquinolone resistance in Salmonella Typhi. 333(7563), 353.3-354.

B Ivanoff, M Levinc (1997) Typhoid Fever Contineuing Challenge from a Resilient foe. 95, 129-142.

S Leume (1999) Multidrug resistant salmonella enteric serotype typhimurium associated with pest and Rodent. 356(1), 21-28.

Dietrich Lorke (1983) A new approach to practical acute toxicity testing. 54(4), 275-287.

A Sofowara (2003) Phytochemical Screening of Nigerian Medicinal Plants Part 11. 44, 234-246.

S Sarkiyayi, J Karago, R Hassan (2011) Studies on Anti Typhoid Properties of Aqueous Methanol Leaves Extract of Albizia ferruginea (Musase). 1(1), 24-30.

G Sciencedomain ; Trease, W Evans (1983) Textbook of Pharmacognosy. 1-100.

K Vivek, S Nandini, S Anitha (2008) Anti Typhoid activity of aqueous extract of fruit peel Citrus sinensis. 2, 49-59.