Effect of Cabergoline Added to Metformin on Glycemic Control, Insulin Resistance and Beta Cell Function in Obese Type 2 Diabetic Patients

Hayder Ch. Assad

Authors

Hayder Ch. Assad

Keywords:

cabergoline, glycemic control, insulin resistance, beta-cell function, obesity, type 2 diabetes

Abstract

The aim of this study is to examine the effect of cabergoline added to metformin on glycemic control, insulin resistance and B-cell function in obese type 2 diabetic patients. Forty obese patients with newly diagnosed type2 diabetes were enrolled in this study and randomized by 1:1 ratio into group (I) receives metformin and group (II) receives metformin plus cabergoline for 12 week. We evaluated fasting plasma glucose (FPG) and postprandial plasma glucose (PPG) every 4 week while body weight, glycosylated hemoglobin, fasting plasma insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and B-cell function (HOMA-B) at the baseline and after 12 week.

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Effect of Cabergoline Added to Metformin on Glycemic Control, Insulin Resistance and Beta Cell Function in Obese Type 2 Diabetic Patients. (2014). Global Journal of Medical Research, 14(B5), 25-31. https://medicalresearchjournal.org/index.php/GJMR/article/view/732

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