Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats
Keywords:
rhus coriaria; indomethacin; water immersion induced ulcer model; ulcer index; post sumaq
Abstract
The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn (HAERC) was investigated in Indomethacin and Water immersion-induced restraint gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. HAERC at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by Indomethacin and Water Immersion restraint method and the results were comparable to the standard treatment regime. We observed that Rhus coriaria Linn extract exhibits significant anti ulcer activity and thus supports the Unani claims about the drug.
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References
H Falcao, J Leite, J Barbosa-Filho, F Athayde-Filho, Chaves (2008) Gastric duodenal antiulcer activity of alkaloids. (13), 3198-3223.
Ross Wilson (2003) Unknown Title. (9), 323.
John Calam, J Baron (2001) Pathophysiology of duodenal and gastric ulcer and gastric cancer. 323(7319), 980-982.
H Humes, Kelley s essentials of internal medicine. 200, 94-99.
J Ledingham, G Warrell, D (2000) Concise Oxford Text book of Medicine. 530-533.
Sandip Bandyopadhyay, Satyesh Pakrashi, Anita Pakrashi (2000) The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer. 70(2), 171-176.
D Raju, K Ilango, V Chitra, Ashish (2009) Evaluation of anti-ulcer activity of methanolic extract of Terminalia chebula fruits in experimental rats. (3), 101-110.
Poonam Dharmani, Pushpesh Mishra, Rakesh Maurya, Vinay Singh Chauhan, Gautam Palit (2005) Allophylus serratus: A plant with potential anti-ulcerogenic activity. 99(3), 361-366.
S Dahnukar, R Kulkarni, N Rege (2000) Pharmacology of Medicinal plants and natural products. (32), 81-S118.
N Ghani, Khazainul Advia (2011) Manish Arora, New Delhi. 826.
E Freirich, E Gehan, D Rall, L Schmidt, H Skipper (1966) Quantitative comprisom of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. 50(4), 219-244.
L Miller, M L Tainter (1944) Estimation of the ED50 and Its Error by Means of Logarithmic-Probit Graph Paper.. 57(2), 261-264.
H Vogel (2002) Drug discovery and evaluation pharmacological Assays, 2nd edi. 869.
Motohiro Hayase, Koji Takeuchi (1986) Gastric acid secretion and lesion formation in rats under water-immersion stress. 31(2), 166-171.
T Brzozowski, S Konturek, S Kwiecien, R Pajdo, I Brzozowski, E Hahn (1998) Involvement of endogenous cholecystokinin and somatostatin in gastro protection induced by intra duodenal fat. 27, 125-137.
B Abu, A Ghaleb, A Dauod, K Safiya, A Advan (2005) Antibacterial activity of Rhus coriaria extracts growing in Palestine. 13(2), 147-153.
J Duke, G Bogenschutz, J Ducellier, Pak Duke (2003) Handbook of Medical Plants. 269-270.
A Jaculin Raiza, Rampratap Meena, S Mageswari, P Meera Devi Sri, R Selvarani, N Zaheer Ahmed (2004) ESTABLISHMENT OF QUALITY STANDARDS OF ABRUS PRECATORIUS L. (ROOT) BY PHYSICOCHEMICAL AND HPTLC METHOD. 8(9), 33-39.
Ahmad Haqeeq, Wadud Abdul, Jahan Nasreen, Hasan Izharul (2013) Anti-ulcer activity of Rhus coriaria in indomethacin and water immersion restraint induced gastric ulcer in experimental rats. 7(3), 61-66.
A Haqeeq, A Wadud, J Nasreen, K Mudasir, S Ghulamuddin (2013) Evaluation of Anti-ulcer activity of hydro alcoholic extract of Post Sumaq (Rhus coriaria Linn.) in Ethanol induced Gastric ulcer in experimental Rats. 1(10), 7-12.
I Sina (2007) Al Qanoon. 3, 446-448.
R Tabri, Firdosul Hikmat (2000) Unknown Title. 1, 197-198.
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2015-01-19
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