Chemistry, Pharmacology and Medicinal Property of Frankincense (Boswellia Species): From the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases.
Keywords:
boswellia species, anti-inflammatory, chronic diseases, cancer, memory enhancement
Abstract
Frankincense, the resinous extract from the trees of the genus Boswellia, has been used for centuries in ceremonial, cosmetic, cultural and as a traditional medicine to treat a variety of ailments especially inflammatory diseases including asthma, arthritis, cerebral edema, chronic pain syndrome, chronic bowel diseases, cancer and some other illnesses. Boswellic acids are the active compounds of frankincense and AKBA (3-O-acetyl-11-keto-β-boswellic acid) is the most important and effective acid among them. Some studies have shown that the use of frankincense can also improve the learning and enhance the memory in animals and human. It seems that frankincense might have a potential ability to be used as an alternative natural medicine not only for chronic and inflammatory diseases but also for the patients with brain and memory disorders.
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
References
Suleiman Afsharypuor, Bahar Nayebzadeh (2005) Essential Oil Constituents of Young Stem, Leaf and Fruit ofPlatycladus orientalis(L.) Franco Grown in Isfahan (Iran). 21(6), 525-528.
H Safayhi, B Rall, E Sailer, H Ammon (1997) Inhibition by Boswellic Acids of Human Leukocyte Elastase. 281, 460-463.
J Yousef (2011) Identifying Frankincense Impact by Biochemical Analysis and Histological Examination on Rats. 18, 189-194.
C Michie, E Cooper (1991) Frankincense and Myrrh as Remedies in Children. 84, 602-605.
M Siddiqul (2011) Boswellia Serrata, a Potential Antiinflammatory Agent: An Overview. 73(3), 255-261.
M Chevrier, A Ryan, D Lee, M Zhongze, Z Wu-Yan, C Via (2005) Boswellia Carterii Extract Inhibits TH1 Cytokines and Promotes TH2 Cytokines in Vitro. 12, 575-580.
Carole Mathe, Jacques Connan, Paul Archier, Michel Mouton, Catherine Vieillescazes (2007) Analysis of Frankincense in Archaeological Samples by Gas Chromatography‐Mass Spectrometry. 97(7), 433-445.
S Shah, I Rathod, B Suhagina, S Pandya, V Parmar (2008) A Simple Highperformance Liquid Chromatographic Method for Estimation of Boswellic Acids from the Market Formulation Containing Boswellia Serrata Extract. 46, 735-738.
M Nusier, H Bataineh, Z Bataineh, H Daradka (2007) Effect of Frankincense (Boswellia thurifera) on Reproductive System in Adult Male Rat. 53(4), 365-370.
Wanzhou Zhao, Frank Entschladen, Hongyan Liu, Bernd Niggemann, Qicheng Fang, Kurt Zaenker, Rui Han (2003) Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. 27(1), 67-75.
H Ammon (2006) Boswellic Acids in Chronic Inflammatory Diseases. 72(12), 1100-1116.
Ahmed Al-Harrasi, Salim Al-Saidi (2008) Phytochemical Analysis of the Essential Oil from Botanically Certified Oleogum Resin of Boswellia sacra (Omani Luban). 13(9), 2181-2189.
Toon Rijkers, Woldeselassie Ogbazghi, Marius Wessel, Frans Bongers (2006) The effect of tapping for frankincense on sexual reproduction in Boswellia papyrifera. 43(6), 1188-1195.
S Goyal, P Sharma, U Ramchandani, S Shivastanva, P Dubey (2011) Novel Anti-Inflammatory Topical Herbal Gels Containing Withania Somnifera and Boswellia Serrata. 2(4), 1087-1094.
A Raja, F Ali, I Khan, A Shawl, D Arora, B Shah, S Taneia (2011) Acetyl-11-Keto-B-boswellic Acid (AKBA): Targeting Oral Cavity Pathogens. 4, 22.
Yasrib Qurishi, Abid Hamid, Parduman Sharma, Zahoor Wani, Dilip Mondhe, Shashank Singh, Mohmmad Zargar, Samar Andotra, Bhahwal Shah, Subhash Taneja, Ajit Saxena (2010) PARP Cleavage and Perturbance in Mitochondrial Membrane Potential by 3-α-Propionyloxy-β-Boswellic Acid Results in Cancer Cell Death and Tumor Regression in Murine Models. 8(7), 867-881.
K Birkner, Boswellia (2006) The Pain Herb.
U Siemoneit, A Koeberle, A Rossi, F Dehm, M Verhoff, S Reckel (2011) Inhibition of Microsomal Prostaglandin E2 Synthase-1 as a Molecular Basis for the Anti-inflammatory Actions of Boswellic Acids from Frankincense. 162, 147-162.
M Samani, H Mahmoodian, A Moghadamnia, Bejeh Mir, A Chitsazan, M (2011) The Effect of Frankincense in the Treatment of Moderate Plaqueinduced Gingivitis: A Double Blinded Randomized Clinical Trial. 19(4), 288-294.
C Cuaz-Perolin, L Billiet, E Bauge, C Copin, D Scott-Algara, F Genze (2008) Antiinflammatory and Antiatherogenic Effects of the NF-kB Inhibitor Acetyl-11-keto-B-Boswellic Acid in LPS-Challenged ApoE-/-Mice. 28, 272-277.
I Gupta, V Gupta, A Parihar, S Gupta, R Lutke, H Safayhi (1998) Effects of Boswellia Serrata Gum Resin in Patients with Bronchial Asthma: results of a Double-blind, Placebo-controlled, 6-week Clinical Study. 3(11), 511-514.
H Eyre, J Hills, D Watkins (2003) Compositions Containing Boswellia Extracts. 6, 516-B517.
Roja Rahimi, M Shams-Ardekani, M Abdollahi (2010) A review of the efficacy of traditional Iranian medicine for inflammatory bowel disease. 16(36), 4504.
Huziafa Salati (2012) Kundur (Boswellia Serrata): Medicinal Importance in Perspective of Unani Medicine and Pharmacological Studies. 14(06), 148-156.
I Gupta, A Parihar, P Malhotra, G Singh, R Ludtke, H Safayhi (1997) Effects of Boswellia Serrata Gum Resin in Patients with Ulcerative Colitis. 2, 37-43.
A Estrada, T Syrovets, K Pitterle, O Lunov, B Buchele, J Schimana-Pfeifer (2010) Tirucallic Acids Are Novel Pleckstrin Homology Domain-Dependent Akt Inhibitors Inducing Apoptosis in Prostate Cancer Cells. 77(3), 378-387.
Lijuan Xia, Duo Chen, Rui Han, Qicheng Fang, Samuel Waxman, Yongkui Jing (2005) Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. 4(3), 381-388.
T Simmet, H Ammon (2001) Use of Boswellic Acid for Treating Brain Tumors. 6, 876-B877.
Kerry Bone (2011) Boswellia and Brain Inflammation. 23.
J Kavitha, J Rossario, J Chandran, P Anbu, Bakkiyanathan (2007) Hypoglycemic and Other Related Effects of Boswellia Glabra in Alloxan-induced Diabetic Rats. 51(1), 29-39.
A Shehata, L Quintanilla-Fend, S Bettio, C Singh, Hpt Ammon (2011) Prevention of Multiple Low-dose Streptozotocin (MLD-STZ) Diabetes in Mice by an Extract from Gum Resin of Boswellia Serrata (BE). 18(12), 1037-1044.
F Ahmadpour, F Namjoyan, M Azemi, M Khodayar, Darvish Padok, A Panahi, M (2012) Antioxidant Capacity and Anti-diabetic Effect of Boswellia Serrata Aqueous Extract in Female Diabetic Rats and the Possible Histological Changes in the Liver and Kidney. 7(5), 17.
Alsaba Raja, Furqan Ali, Inshad Khan, Abdul Shawl, Daljit Arora, Bhahwal Shah, Subhash Taneja (2011) Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-β-boswellic acid from Boswellia serrata. 11(1).
Mahmoud Hosseini, Mosa Al-Reza Hadjzadeh, Mohammad Derakhshan, Shahrzad Havakhah, Fatemeh Rassouli, Hassan Rakhshandeh, Fatema Saffarzadeh (2009) The beneficial effects of olibanum on memory deficit induced by hypothyroidism in adult rats tested in Morris water maze. 33(3), 463-468.
B Rao, M Shivalingam, Kpr Chowdary, N Sunitha, V Rao (2012) Preparation and Evaluation for Controlled Release of Olibanum Resin Coated Microcapsules of Carbamazepine. 3(2), 71-76.
(2010) The Beneficial Effects of Olibanum on Memory Deficit Induced by Hypothyroidism in Adult Rats Tested in Morris Water Maze. 33(3), 463-468.
M Sharifabad, E Esfandiari, H Alaei (2004) Effects of Frankincense Aqueous Extract during Gestational Period on Increasing Power of Learning and Memory in Adult Offsprings. 21(71), 16-20.
M Sharifabad, E Esfandiari (2007) A Morphometeric Study on CA3 Hippocampal Field in Young Rats following Maternal Administration of Boswellia Serrata Resin during Gestation. 10(3), 176-182.
M Sharifabad, E Esfandiari (2011) Effect of Boswellia Serrata Triana & Planch. Gum Resin Administration during Lactation on Morphology of Pyramidal Neurones in Hippocampus of Rat. 2(1), 45-52.
Kpr Chowdary, P Mohapatra, M Murali Krishna (2012) Evaluation of olibanum and its resin as rate controlling matrix for controlled release of diclofenac. 68(4), 497.
Kpr Chowdary, P Mohapatra, M Murali Krishna (2006) Evaluation of olibanum resin as microencapsulating agent for controlled drug delivery. 68(4), 461.
Published
2015-07-30
Issue
Section
License
Copyright (c) 2015 Authors and Global Journals Private Limited

This work is licensed under a Creative Commons Attribution 4.0 International License.