Potential Effects of a Herbal Remedy

Authors

  • Kporou Kouassi Elisée

  • Gbogbo Moussa

  • Yao Akissi Nadège

  • Tanoh Aya Honorine

  • Traore Aboubakar

  • Kroa Ehoule

Keywords:

activity, antioxidant, antihyperglycemic, medicine, plant

Abstract

This study aimed to evaluate antihyperglycemic and antioxidant activities of an herbal medicinal product codified "DD3". From dry aqueous extract, the differents tests were carried out. Phytochemical screening showed presence of alkaloids, polyphenols, flavonoids, saponosides, sterols and terpens. Regarding antioxidant activities, DPPH test showed that DD3 remedy (IC50= 59.39 ± 0.69 µg/mL) had a lower antioxidant potential than vitamin C (IC50= 7.93 ± 0.45 µg/ mL), and that was identical for ABTS test for which IC50 = 94.34 ± 0.73 µg/mL for the Remedy against IC50= 25.87 ± 0.46 µg/mL for Gallic acid. About antihyperglycaemic test, unlike glibenclamide which induced hypoglycaemia after 3 hours, the remedy at 500 mg/kg bw brings blood sugar levels back to normal values after this time. The DD3 remedy could be used as a blood sugar regulator.

How to Cite

Potential Effects of a Herbal Remedy. (2023). Global Journal of Medical Research, 22(B3), 35-42. https://medicalresearchjournal.org/index.php/GJMR/article/view/102273

References

J Sehonou, B Addra, L Houessinon, N Kodjoh (2005) Phytobézoard gastrique favorisé par la pharmacopée traditionnelle africaine et les antisécrétoires: un cas. 35(S1), 489-491.

M Elliott, K Chithan, T Theorides (2000) The effects of plant flavonoids on Mammalian cells: implications for inflammation, Heart disease, and Cancer. 52(4), 673-751.

Hu Fenglin, Lu Ruili, Huang Bao, Ming Liang (2004) Free radical scavenging activity of extracts prepared from fresh leaves of selected Chinese medicinal plants. 75(1), 14-23.

Fid (2019) FID. 167.

R Cherif, A Kemassi, Z Boual, N Bouziane, F Benbrahim, A Hadjseyd, T Gharib, A Ould El Hadj-Khelil, M Sakeur, M Ould El Hadj (2015) Activités biologiques des extraits aqueux de Pergularia tomentosa L. (Asclepiadaceae). 17(1), 25-35.

M Katemo, P Mpiana, B Mbala, S Mihigo, K Ngbolua, D Tshibangu, P Koyange (2012) Ethnopharmacological survey of plants used against diabetes in Kisangani city (DR Congo). 144, 39-43.

Brahima Soro, Isidore Kouadio Kpandji, Sylvain Zadi Bopo, Adama Bem, Didier Paulin Sokouri (2018) PERFORMANCES DE CROISSANCE DES POPULATIONS DE TROIS SOUCHES DE CAILLE JAPONAISE (COTURNIXJAPONICA, TEMMINCK SCHLEGEL,1848 NT) ELEVEES A LA SOCIETE AGROPISCICOLE DE LA ME DADZOPE (COTE DIVOIRE). 12(12), 676-684.

F Kouassi, C Koman, A Kra, M Soumahoro, T Sowagnon, R N'dohi (2021) Epidemiological Features of Diabetic Retinopathy in Abidjan (Côte d'Ivoire): A Study about 448 Patients. 08(03), 140-149.

F Lacopini, A Dormeier, T Masunda (2008) Activité anti-hyperglycemique et antiradicalaire des extraits des fruits de Raphia gentiliana (Aecaceae). 8(6), 2441-2451.

E Lawson, G Eklu (1997) Activité hypoglycémiante de quelques plantes médicinales. 1(9), 60-79.

L Leong, G Shui (2002) Polyphenols, Carotenoids, Vitamin C Content in tropical Fruits and Vegetables and Impacts of Processing Methods an Investigation of Antioxidant Capacity of Fruits in Singapore Markets. 76, 69-75.

O Nacoulma (1996) Plantes médicinales et Pratiques médicales Traditionnelles au Burkina Faso: cas du plateau central T1 & T2. 158.

Oms (2014) OMS : Une charte pour garantir la sécurité des agents de santé pour assurer celle des patients. nº357(6), 86-86.

Dario Pitocco, Francesca Martini, Giuseppe Scavone, Francesco Zaccardi, Giovanni Ghirlanda (2014) Oxidative Stress and Diabetes. 3283-3317.

Ulf Risérus, Walter Willett, Frank Hu (2009) Dietary fats and prevention of type 2 diabetes. 48(1), 44-51.

N Tietz (1987) Fundamentals of Clinical Chemistry. 427.

J Torres, Gonzalo Velazquez (2005) Commercial opportunities and research challenges in the high pressure processing of foods. 67(1-2), 95-112.

G Trease, S Evans (2002) Pharmacognosy. 35.

X Zhang, B Tan (2000) Propriété Antidiabétique de l'extrait éthanolique de Paniculata chez les rats rendus diabétiques à la streptozotocine. 21, 157-173.

A Diomandé, K Yao, Y Sylla, B Tra, A Bakayoko, M Kone (2018) Pouvoir antioxydant et teneurs en composés phénoliques de deux espèces du genre Albertisia: Albertisia cordifolia (Mangenot & J. Miège) Forman et Albertisia scandens (Mangenot & J. Miège) Forman (Menispermaceae). 14(30), 128-144.

Potential Effects of a Herbal Remedy

Published

2023-02-11

How to Cite

Potential Effects of a Herbal Remedy. (2023). Global Journal of Medical Research, 22(B3), 35-42. https://medicalresearchjournal.org/index.php/GJMR/article/view/102273