Biochemical Changes of Mancozeb-Induced AlteBiochemical Changes of Mancozeb-Induced Alternations in Testes and Thyroid gland of Male Ratsrnations in Testes and Thyroid gland of Male Rats
Keywords:
mancozeb, rats, thyroid glands, testes, histology
Abstract
Mancozeb manganese ethylene bis dithiocarbamate polymeric complex -with zinc salts is a very important protective non-systemic fungicide, classified as an ethylene bis dithiocarbamate fungicide. Mancozeb used for controlling fungal diseases for a wide variety of crops because of its broad-spectrum as fungicidal effects and high compatibility with agrochemicals. The objective of this study was to investigate the results of the fungicide mancozeb at different doses on some biochemical parameters, reproductive performance, and histological changes in testes and thyroid gland. The low amount equals 1/7 of LD 50 manczeb-d 1 , and the high amount equals 1/3.5 of LD 50 mancozeb-d 1 . Amounts of mancozeb (mancozeb-d1 and mancozeb-d 2 ) adjusted according to the rat's body weights. The results showed that mancozeb decreased plasma testosterone level, sperm count, viability, motility, and significantly (P
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2022-07-09
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